Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6830548 | 0.66 | SLC18A3 (0.37) | ALDH1A1HPGDKDM4ETDP1 | |
| SCHEMBL16226181 | 0.65 | TSHR (0.37) | LMNA | |
| Iodide SCHEMBL11457678 | 0.62 | SLC18A3 (0.37) | — | |
| SCHEMBL9629659 | 0.61 | MEN1 (0.46) | ALDH1A1HPGDGAAALOX12LMNA | |
| SCHEMBL21291833 | 0.60 | ATM (0.48) | ALDH1A1HPGDGAAALOX12LMNA | |
| SCHEMBL7363290 | 0.59 | CYP19A1 (0.43) | GAAALOX12 | |
| SCHEMBL7358273 | 0.59 | CYP19A1 (0.43) | GAAALOX12 | |
| SCHEMBL7359734 | 0.59 | CYP19A1 (0.43) | GAAALOX12 | |
| SCHEMBL26858805 | 0.59 | SLC18A3 (0.36) | — | |
| SCHEMBL26860300 | 0.59 | SLC18A3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030909-A4 | IMMUNE ACTIVATION BY DOUBLE-STRANDED POLYNUCLEOTIDES | SENTRON MEDICAL INC (US) | 2005-11-16 | — | — | EP | disclosed |
| EP-1030909-A1 | IMMUNE ACTIVATION BY DOUBLE-STRANDED POLYNUCLEOTIDES | KOHN, Leonard D. (US) | 2000-08-30 | — | — | EP | disclosed |
| WO-2000015768-A1 | IMMUNE ACTIVATION BY DOUBLE-STRANDED POLYNUCLEOTIDES | KOHN LEONARD D (US) | 2000-03-23 | — | — | WO | disclosed |