Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | SQLE | Q14534 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL4421233 | 1.00 | MAPT (0.40) | MAPTPOLBCA2CA1CES2 | |
| SCHEMBL13885154 | 0.99 | MAPT (0.41) | MAPTPOLBCA2CA1CES2 | |
| SCHEMBL4421229 | 0.86 | MAPT (0.40) | MAPTPOLBCA2CA1CES2 | |
| Ammonia Solution, Strong SCHEMBL4419736 | 0.82 | CA1 (0.44) | MAPTPOLBCA2CA1CES2 | |
| Ammonia Solution, Strong SCHEMBL4421010 | 0.82 | CA2 (0.41) | MAPTPOLBCA2CA1CES2 | |
| SCHEMBL1686914 | 0.81 | CA2 (0.42) | MAPTPOLBCA2CA1CES2 | |
| Ammonia Solution, Strong SCHEMBL4430062 | 0.79 | MEN1 (0.36) | MAPTPOLBCA2CA1CES2 | |
| Ammonia Solution, Strong SCHEMBL4421234 | 0.78 | MEN1 (0.38) | MAPTPOLBCA2CA1CES2 | |
| SCHEMBL4421232 | 0.77 | CA2 (0.36) | MAPTPOLBCA2CA1CES2 | |
| SCHEMBL7705155 | 0.77 | CA2 (0.48) | CA2SQLELMNACYP1A2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194436-B1 | SULFONAMIDOMETHYL PHOSPHONATE INHIBITORS OF BETA-LACTAMASE | METHYLGENE INC (CA) | 2005-11-30 | — | — | EP | disclosed |