Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | CASP6 | P55212 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | APAF1 | O14727 | 1/20 | 0.57 |
| ▸ | GRK2 | P25098 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29832117 | 1.00 | GAA (0.77) | GAACYP2C19TSHRALDH1A1KMT2A | |
| SCHEMBL9312776 | 0.88 | GAA (0.84) | GAACYP2C19TSHRALDH1A1KMT2A | |
| SCHEMBL5188518 | 0.87 | GAA (0.81) | GAACYP2C19TSHRALDH1A1KMT2A | |
| SCHEMBL27103373 | 0.84 | GAA (0.77) | GAACYP2C19TSHRALDH1A1KMT2A | |
| SCHEMBL18101767 | 0.84 | GAA (0.77) | GAACYP2C19TSHRALDH1A1KMT2A | |
| SCHEMBL8752422 | 0.84 | GAA (0.77) | GAACYP2C19TSHRALDH1A1KMT2A | |
| SCHEMBL30634403 | 0.84 | GAA (0.77) | GAACYP2C19TSHRALDH1A1KMT2A | |
| SCHEMBL31146391 | 0.83 | ALDH1A1 (0.65) | TSHRALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL9191016 | 0.83 | ALDH1A1 (0.65) | TSHRALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL8110954 | 0.83 | GAA (0.75) | GAACYP2C19TSHRALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024043242-A1 | HEART FAILURE TREATMENT VIA CARDIOTONIC EFFECT BY TRPC3/6/7 CHANNEL ACTIVATION | 国立大学法人九州大学 | 2024-02-29 | — | — | WO | disclosed |
| WO-2023233994-A1 | PHARMACEUTICAL COMPOSITION AND AUTOPHAGY ACTIVATOR | 国立大学法人京都大学 | 2023-12-07 | — | — | WO | disclosed |
| WO-2022118966-A1 | AGENT FOR PROMOTING NUCLEIC ACID MOLECULE UPTAKE INTO CELLS, PHARMACEUTICAL COMPOSITION, AND NOVEL COMPOUND | 国立大学法人京都大学 | 2022-06-09 | — | — | WO | disclosed |
| CN-108276323-B | 3-functionalized N (O, S) -heteroandene derivatives and application thereof in respiratory syncytial virus resistance | 北京交通大学 | 2020-12-29 | — | — | CN | disclosed |
| WO-2014192865-A1 | PHENYLPIPERAZINE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2014-12-04 | — | — | WO | disclosed |
| EP-1212056-B1 | METHODS AND COMPOSITIONS FOR BISUBSTRATE INHIBITORS OF ACETYLTRANSFERASES | US GOV HEALTH & HUMAN SERV (US) | 2005-12-07 | — | — | EP | disclosed |
| EP-1212056-A1 | METHODS AND COMPOSITIONS FOR BISUBSTRATE INHIBITORS OF ACETYLTRANSFERASES | The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2002-06-12 | — | — | EP | disclosed |
| US-20020002144-A1 | Methods and compositions for bisubstrate inhibitors of acetyltransferases | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2002-01-03 | — | — | US | disclosed |
| WO-2001012185-A1 | METHODS AND COMPOSITIONS FOR BISUBSTRATE INHIBITORS OF ACETYLTRANSFERASES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2001-02-22 | — | — | WO | disclosed |