⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7032028 | 0.78 | — | — | |
| SCHEMBL27407006 | 0.78 | — | — | |
| SCHEMBL28483687 | 0.72 | — | — | |
| SCHEMBL30140506 | 0.67 | ALDH1A1 (0.36) | — | |
| SCHEMBL29543033 | 0.67 | ALDH1A1 (0.36) | — | |
| SCHEMBL28413193 | 0.67 | — | — | |
| SCHEMBL1818549 | 0.67 | — | — | |
| SCHEMBL8628095 | 0.67 | — | — | |
| SCHEMBL20594183 | 0.65 | — | — | |
| SCHEMBL19837712 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230130617-A1 | PROCESS FOR IMPROVED OPIOID SYNTHESIS | RHODES TECHNOLOGIES (US) | 2023-04-27 | — | — | US | disclosed |
| CN-111544196-A | Glaucoma aqueous humor drainage device and preparation method thereof | 上海昊海生物科技股份有限公司 | 2020-08-18 | — | — | CN | disclosed |
| EP-2880033-B1 | CYCLIC UREA- OR LACTAM-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND THE USES THEREOF | PURDUE PHARMA LP (US) | 2020-06-17 | — | — | EP | disclosed |
| US-10316042-B2 | Process for improved opioid synthesis | RHODES TECHNOLOGIES (US) | 2019-06-11 | — | — | US | disclosed |
| US-10118927-B2 | Substituted piperidin-4-amino-type compounds and uses thereof | PURDUE PHARMA L.P. (US) | 2018-11-06 | — | — | US | disclosed |
| US-9963458-B2 | Indole and indoline-type piperidine compounds and uses thereof | PURDUE PHARMA L.P. (US) | 2018-05-08 | — | — | US | disclosed |
| US-9951038-B2 | Quinazolin-4(3H)-one-type piperidine compounds and uses thereof | PURDUE PHARMA L.P. (US) | 2018-04-24 | — | — | US | disclosed |
| US-9873691-B2 | TRPV1 antagonists including dihydroxy substituent and uses thereof | PURDUE PHARMA L.P. (US) | 2018-01-23 | — | — | US | disclosed |
| EP-2872516-B1 | PROCESS FOR IMPROVED OPIOID SYNTHESIS | RHODES TECH (US) | 2017-08-30 | — | — | EP | disclosed |
| US-9598411-B2 | Substituted benzimidazole-type piperidine compounds and uses thereof | PURDUE PHARMA L.P. (US) | 2017-03-21 | — | — | US | disclosed |
| WO-2013021276-A1 | TRPV1 ANTAGONISTS INCLUDING DIHYDROXY SUBSTITUENT AND USES THEREOF | PURDUE PHARMA L.P. (US) | 2013-02-14 | — | — | WO | disclosed |
| WO-2012085648-A1 | PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF | PURDUE PHARMA L.P. (US) | 2012-06-28 | — | — | WO | disclosed |
| EP-1055696-B1 | Rubber powder containing high levels of fillers, method for the production and use thereof | PKU PULVERKAUTSCHUK UNION GMBH (DE) | 2005-10-19 | — | — | EP | disclosed |
| US-6822036-B1 | SURFACE OF OXIDIC OR SILICA FILLERS MODIFIED WITH AN ORGANOSILICON COMPOUND | PKU PULVERKAUTSCHUK UNION GMBH (DE) | 2004-11-23 | — | — | US | disclosed |
| US-6340724-B1 | SILICON CONTAINING FILLERS FOR RUBBERS IN POWDER FORM | PKU PULVERKAUTSCHUK UNION GMBH (GB) | 2002-01-22 | — | — | US | disclosed |
| US-6309796-B1 | PHOTORESISTS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1055696-A1 | Rubber powder containing high levels of fillers, method for the production and use thereof | PKU Pulverkautschuk Union GmbH (DE) | 2000-11-29 | — | — | EP | disclosed |
| EP-0177674-B1 | SURFACE-MODIFIED SYNTHETIC SILICA FILLERS, A PREPARATION METHOD AND THEIR USE | Degussa Aktiengesellschaft (DE) | 1990-08-29 | — | — | EP | disclosed |
| US-4704414-A | WATER INSOLUBLE SILICON-CONTAINING POLYSULFIDES | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1987-11-03 | — | — | US | disclosed |
| US-4278587-A | HALOALKYLSILANE | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |