Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 18/20 | 0.71 |
| ▸ | ITGB3 | P05106 | 17/20 | 0.71 |
| ▸ | ITGB6 | P18564 | 5/20 | 0.57 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.57 |
| ▸ | ITGB8 | P26012 | 4/20 | 0.57 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.55 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.55 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7377654 | 0.99 | ITGAV (0.69) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL13720083 | 0.96 | ITGAV (0.69) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL5500945 | 0.90 | ITGAV (0.67) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL22029444 | 0.87 | ITGB3 (0.90) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL7549076 | 0.86 | ITGB3 (0.74) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL24363119 | 0.85 | ITGB3 (0.73) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL21706071 | 0.84 | ITGB3 (0.90) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL25350666 | 0.84 | ITGAV (0.66) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL15397316 | 0.84 | ITGB3 (0.79) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL3219843 | 0.83 | ITGAV (0.65) | ITGAVITGB3ITGB6ITGB5ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B1 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2005-05-25 | — | — | EP | disclosed |
| WO-2002051810-A2 | INTEGRIN RECEPTOR LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2002-07-04 | — | — | WO | disclosed |