Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.45 |
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CALML3 | P27482 | 1/20 | 0.45 |
| ▸ | SDHA | P31040 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 6/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6426468 | 1.00 | MAOB (0.45) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6338402 | 0.80 | MAOB (0.60) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6478092 | 0.80 | MAOA (0.70) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6337870 | 0.80 | MAOA (0.70) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL8592444 | 0.72 | MAOB (0.71) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL8592442 | 0.72 | MAOB (0.71) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6110851 | 0.70 | MAOA (0.62) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6338191 | 0.70 | MAOA (0.75) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL18409560 | 0.70 | MAOA (0.61) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL6339543 | 0.70 | MAOA (0.68) | MAOBMAOALMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385834-B1 | BICYCLO[3,1,0]HEXANE CONTAINING OXAZOLIDINONE ANTIBIOTIC AND DERIVATIVES THEREOF | MERCK & CO INC (US) | 2005-09-14 | — | — | EP | disclosed |