Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 3/20 | 0.68 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.68 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.68 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.56 |
| ▸ | NSD2 | O96028 | 2/20 | 0.52 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.52 |
| ▸ | AHCY | P23526 | 6/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179434 | 0.81 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL1924594 | 0.78 | ADORA2A (1.00) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL5180847 | 0.78 | PI4KA (0.68) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL11222112 | 0.78 | ADORA2A (0.80) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL22016921 | 0.77 | PI4KA (0.75) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL12925855 | 0.76 | ADORA2A (0.71) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL1871838 | 0.75 | ADORA2A (0.75) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL22558037 | 0.75 | ADORA2A (0.69) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL2495370 | 0.75 | ADORA2A (0.69) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL5180872 | 0.74 | ADORA2A (0.66) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501850-A2 | NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | GENELABS TECHNOLOGIES, INC. (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2003093290-A2 | NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | GENELABS TECHNOLOGIES, INC. (US) | 2003-11-13 | — | — | WO | claimed |