SCHEMBL6426620

SCHEMBL6426620

O=C(O)C1(C(=O)O)C=c2oc3ccccc3c2=CC1(C(=O)O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
USP2 O75604 1/20 0.39
CSNK2A2 P19784 1/20 0.39
PTGS1 P23219 1/20 0.39
CSNK2B P67870 1/20 0.39
CSNK2A1 P68400 1/20 0.39
CSNK2A3 Q8NEV1 1/20 0.39
MAPT P10636 3/20 0.37
NPC1 O15118 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP3A4 P08684 2/20 0.37
GLA P06280 2/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MAOA P21397 2/20 0.37
ALDH1A1 P00352 1/20 0.37
PGAM1 P18669 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11395298 0.68 KDM4E (0.33) KDM4EMAPTCYP3A4GLAHPGD
Dibenzofuran SCHEMBL9651343 0.67 KDM4E (0.61) KDM4EUSP2CSNK2A2PTGS1CSNK2B
Dibenzofuran SCHEMBL7810840 0.67 KDM4E (0.61) KDM4EUSP2CSNK2A2PTGS1CSNK2B
Dibenzofuran SCHEMBL9826947 0.64 KDM4E (0.56) KDM4EUSP2CSNK2A2PTGS1CSNK2B
SCHEMBL12110363 0.61 KDM4E (0.32) KDM4EMAPTCYP3A4GLAHPGD
Dibenzofuran SCHEMBL28169618 0.61 KDM4E (0.65) KDM4EUSP2CSNK2A2PTGS1CSNK2B
Xanthone SCHEMBL10868526 0.61 MAOA (0.69) KDM4EMAPTNPC1KMT2ACYP3A4
SCHEMBL16500762 0.60 KDM4E (0.40) KDM4EMAPTNPC1KMT2ACYP3A4
Dibenzofuran SCHEMBL28504417 0.60 MAOA (0.50) KDM4EUSP2CSNK2A2PTGS1CSNK2B
Dibenzofuran SCHEMBL10336261 0.60 KDM4E (0.50) KDM4EUSP2CSNK2A2PTGS1CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2672614-A1 ELECTRICALLY INSULATING RESIN SHEET FOR MOTORS AND PROCESS FOR PRODUCTION THEREOF Nitto Denko Corporation (JP) 2013-12-11 EP disclosed
US-20130309481-A1 ELECTRICALLY INSULATING RESIN SHEET FOR MOTORS AND PROCESS FOR PRODUCTION THEREOF NITTO DENKO CORPORATION (JP) 2013-11-21 US disclosed
US-20130209741-A1 POROUS RESIN SHEET AND METHOD FOR PRODUCING THE SAME NITTO DENKO CORPORATION (JP) 2013-08-15 US disclosed
US-6939614-B2 Image-fixing member, image-fixing apparatus and image-forming apparatus using the same RICOH COMPANY, LTD. (JP) 2005-09-06 US disclosed
US-20040033431-A1 Image-fixing member, image-fixing apparatus and image-forming apparatus using the same RICOH COMPANY, LTD. (JP) 2004-02-19 US disclosed