Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | EIF4E | P06730 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157537 | 0.85 | ALDH1A1 (0.33) | CYP3A4MAPTEIF4EALDH1A1 | |
| SCHEMBL6426834 | 0.84 | EIF4E (0.34) | CYP3A4PDK1EIF4EALDH1A1 | |
| SCHEMBL3810195 | 0.79 | CYP3A4 (0.34) | CYP3A4TSHRMAPTPDK1TP53 | |
| SCHEMBL2157423 | 0.68 | CYP3A4 (0.37) | CYP3A4 | |
| SCHEMBL2158082 | 0.66 | NPC1 (0.34) | CYP3A4ATMALDH1A1 | |
| SCHEMBL2158053 | 0.65 | CYP3A4 (0.43) | CYP3A4PDK1 | |
| SCHEMBL2158321 | 0.65 | CYP3A4 (0.47) | CYP3A4MAPTPDK1 | |
| SCHEMBL2157844 | 0.63 | CYP1A2 (0.41) | CYP3A4TSHR | |
| SCHEMBL14950511 | 0.62 | CYP1A2 (0.40) | CYP3A4MAPTTP53 | |
| SCHEMBL14136663 | 0.62 | CYP1A2 (0.38) | CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881741-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC. (CA) | 2005-04-19 | — | — | US | claimed |