Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.61 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.61 |
| ▸ | FDPS | P14324 | 11/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1533943 | 0.77 | LPAR1 (0.96) | LPAR3LPAR1FDPSGGPS1SMPD1 | |
| SCHEMBL193245 | 0.76 | LPAR1 (1.00) | LPAR3LPAR1FDPSGGPS1SMPD1 | |
| SCHEMBL6427229 | 0.74 | LPAR1 (0.68) | LPAR3LPAR1FDPSGGPS1SMPD1 | |
| SCHEMBL24067449 | 0.73 | GGPS1 (0.48) | LPAR3LPAR1FDPSGGPS1SMPD1 | |
| SCHEMBL25873393 | 0.73 | GGPS1 (0.48) | LPAR3LPAR1FDPSGGPS1SMPD1 | |
| Dodecane SCHEMBL28904661 | 0.72 | LPAR3 (0.56) | LPAR3FDPSGGPS1LPAR2 | |
| SCHEMBL28533054 | 0.72 | LPAR3 (0.56) | LPAR3FDPSGGPS1LPAR2 | |
| SCHEMBL29164627 | 0.72 | LPAR3 (0.56) | LPAR3FDPSGGPS1LPAR2 | |
| Hexane SCHEMBL25299261 | 0.72 | LPAR3 (0.50) | LPAR3FDPSGGPS1LPAR2 | |
| Tridecane SCHEMBL5319320 | 0.72 | LPAR3 (0.56) | LPAR3FDPSGGPS1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6943267-B1 | compounds structurally resemble the substrates of the enzymes, but have nonhydrolyzable mono protonated thiophosphonate salts; chromatography or distillations not required | UTAH STATE UNIVERSITY (US) | 2005-09-13 | — | — | US | disclosed |