Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 1/20 | 0.68 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.68 |
| ▸ | FDPS | P14324 | 11/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1533943 | 0.83 | LPAR1 (0.96) | LPAR1LPAR3FDPSGGPS1SMPD1 | |
| SCHEMBL193245 | 0.81 | LPAR1 (1.00) | LPAR1LPAR3FDPSGGPS1SMPD1 | |
| SCHEMBL1533877 | 0.76 | LPAR1 (0.83) | LPAR1LPAR3FDPSGGPS1SMPD1 | |
| SCHEMBL6427233 | 0.74 | LPAR3 (0.61) | LPAR1LPAR3FDPSGGPS1SMPD1 | |
| SCHEMBL21835985 | 0.74 | LPAR1 (0.67) | LPAR1LPAR3FDPSGGPS1SMPD1 | |
| SCHEMBL17476332 | 0.72 | LPAR1 (0.70) | LPAR1LPAR3FDPSGGPS1SMPD1 | |
| SCHEMBL21101672 | 0.71 | LPAR1 (0.68) | LPAR1LPAR3FDPSGGPS1SMPD1 | |
| Hexane SCHEMBL28170879 | 0.69 | LPAR3 (0.57) | LPAR1LPAR3FDPSGGPS1 | |
| SCHEMBL8672279 | 0.69 | FDPS (0.64) | LPAR1LPAR3FDPSGGPS1SMPD1 | |
| Phosphoric Acid SCHEMBL27450836 | 0.68 | FDPS (0.52) | LPAR1LPAR3FDPSGGPS1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6943267-B1 | compounds structurally resemble the substrates of the enzymes, but have nonhydrolyzable mono protonated thiophosphonate salts; chromatography or distillations not required | UTAH STATE UNIVERSITY (US) | 2005-09-13 | — | — | US | disclosed |