Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.65 |
| ▸ | MAOB | P27338 | 3/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | SDHA | P31040 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CALML3 | P27482 | 1/20 | 0.61 |
| ▸ | F10 | P00742 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4972481 | 0.89 | MAOA (0.72) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL4972471 | 0.89 | MAOA (0.72) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6426220 | 0.88 | MAOA (0.60) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6162524 | 0.87 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6160326 | 0.87 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6160328 | 0.87 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7195331 | 0.87 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6161177 | 0.87 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7851050 | 0.86 | MAOA (0.64) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5739119 | 0.86 | MAOA (0.63) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301207-B1 | COMPOSITIONS FOR TREATING BACTERIAL INFECTIONS, CONTAINING AN OXAZOLIDINONE COMPOUND, SULBACTAM AND AND AMPICILLIN | PHARMACIA & UPJOHN CO LLC (US) | 2005-08-10 | — | — | EP | claimed |
| EP-0856002-B1 | PHENYLOXAZOLIDINONES HAVING A C-C BOND TO 4-8 MEMBERED HETEROCYCLIC RINGS | UPJOHN CO (US) | 2001-10-24 | — | — | EP | claimed |