Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.64 |
| ▸ | NAALAD2 | Q9Y3Q0 | 5/20 | 0.64 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.64 |
| ▸ | GNPAT | O15228 | 1/20 | 0.50 |
| ▸ | GGH | Q92820 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427496 | 1.00 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL14719913 | 0.85 | FOLH1 (0.72) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL14310838 | 0.85 | FOLH1 (0.72) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL14729416 | 0.85 | FOLH1 (0.72) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL6429176 | 0.85 | KMT2A (0.48) | FOLH1NAALAD2RIMKLAGNPAT | |
| SCHEMBL6429173 | 0.85 | KMT2A (0.48) | FOLH1NAALAD2RIMKLAGNPAT | |
| SCHEMBL4572551 | 0.83 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL1533825 | 0.83 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL6270974 | 0.83 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL6307131 | 0.82 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLAGNPATGGH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212056-B1 | METHODS AND COMPOSITIONS FOR BISUBSTRATE INHIBITORS OF ACETYLTRANSFERASES | US GOV HEALTH & HUMAN SERV (US) | 2005-12-07 | — | — | EP | disclosed |