SCHEMBL6270974

SCHEMBL6270974

O=C(O)CCC(=O)NC(CCC(=O)O)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 7/20 0.69
NAALAD2 Q9Y3Q0 3/20 0.69
RIMKLA Q8IXN7 1/20 0.69
GNPAT O15228 1/20 0.68
NOD1 Q9Y239 1/20 0.51
KDM4E B2RXH2 2/20 0.50
KDM6B O15054 1/20 0.50
KDM5C P41229 1/20 0.50
EGLN1 Q9GZT9 1/20 0.50
PHF8 Q9UPP1 1/20 0.50
KDM2A Q9Y2K7 1/20 0.50
EPHX2 P34913 1/20 0.49
GGH Q92820 1/20 0.48
HPGD P15428 1/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1533825 1.00 FOLH1 (0.69) FOLH1NAALAD2RIMKLAGNPATNOD1
SCHEMBL14310838 0.98 FOLH1 (0.72) FOLH1NAALAD2RIMKLAGNPATNOD1
SCHEMBL27584107 0.89 FOLH1 (0.67) FOLH1NAALAD2RIMKLAGNPATNOD1
SCHEMBL16350092 0.89 FOLH1 (0.67) FOLH1NAALAD2RIMKLAGNPATNOD1
SCHEMBL14719913 0.89 FOLH1 (0.72) FOLH1NAALAD2RIMKLAGNPATKDM4E
SCHEMBL14729416 0.89 FOLH1 (0.72) FOLH1NAALAD2RIMKLAGNPATKDM4E
SCHEMBL7046532 0.88 GNPAT (0.65) FOLH1NAALAD2RIMKLAGNPATNOD1
SCHEMBL17384176 0.88 FOLH1 (0.60) FOLH1NAALAD2RIMKLAGNPATNOD1
SCHEMBL17384133 0.88 FOLH1 (0.60) FOLH1NAALAD2RIMKLAGNPATNOD1
SCHEMBL19203698 0.88 FOLH1 (0.60) FOLH1NAALAD2RIMKLAGNPATNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115175759-A Polyamide microcapsules 弗门尼舍有限公司 2022-10-11 CN disclosed
US-20120231972-A1 Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same INSTITUTE OF CATALYSIS (CSIC) (ES) 2012-09-13 US disclosed
WO-2010105851-A1 PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-23 WO disclosed
EP-1599103-A1 AMINOACID DERIVATIVES OF DICARBOXYLIC ACIDS AS FLAVOR INGREDIENTS FIRMENICH SA (CH) 2005-11-30 EP disclosed
US-20050233058-A1 Aminoacid derivatives of dicarboxylic acids as flavor ingredients FIRMENICH SA (CH) 2005-10-20 US disclosed
WO-2004075663-A1 AMINOACID DERIVATIVES OF DICARBOXYLIC ACIDS AS FLAVOR INGREDIENTS FIRMENICH SA (CH) 2004-09-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120231972-A1 Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same SI, GUSB, MPI FOLH1 185/4885NAALAD2 108/4885RIMKLA 1480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.