Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495007 | 1.00 | TRPV1 (0.40) | TRPV1EPHX2KDM5AKDM5BTRPM8 | |
| SCHEMBL5500964 | 0.89 | USP30 (0.51) | USP30EPHX1 | |
| SCHEMBL5499584 | 0.86 | HDAC1 (0.39) | KDM4ETSHRUSP30 | |
| SCHEMBL5497058 | 0.86 | HDAC1 (0.39) | KDM4ETSHRUSP30 | |
| SCHEMBL5496605 | 0.86 | HDAC1 (0.39) | KDM4ETSHRUSP30 | |
| SCHEMBL5493786 | 0.83 | USP30 (0.42) | TRPV1USP30 | |
| SCHEMBL27620821 | 0.82 | HDAC3 (0.49) | USP30 | |
| SCHEMBL6430075 | 0.82 | HDAC3 (0.49) | USP30 | |
| SCHEMBL5493346 | 0.80 | HDAC1 (0.35) | TRPV1KDM4E | |
| SCHEMBL5500438 | 0.80 | KMT2A (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556389-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039814-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2004-05-13 | — | — | WO | disclosed |