Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.94 |
| ▸ | MAPT | P10636 | 3/20 | 0.94 |
| ▸ | HPGD | P15428 | 3/20 | 0.94 |
| ▸ | GLA | P06280 | 2/20 | 0.94 |
| ▸ | ACHE | P22303 | 1/20 | 0.94 |
| ▸ | HTR3A | P46098 | 1/20 | 0.62 |
| ▸ | NQO2 | P16083 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridine SCHEMBL31147979 | 1.00 | ALDH1A1 (0.94) | ALDH1A1MAPTHPGDGLAACHE | |
| Acridine SCHEMBL462843 | 1.00 | ALDH1A1 (0.94) | ALDH1A1MAPTHPGDGLAACHE | |
| Acridine SCHEMBL28062881 | 0.97 | MAPT (0.88) | ALDH1A1MAPTHPGDGLAACHE | |
| Acridine SCHEMBL4972293 | 0.97 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDGLAACHE | |
| Acridine SCHEMBL3045498 | 0.97 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDGLAACHE | |
| Acridine SCHEMBL1772714 | 0.97 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDGLAACHE | |
| Acridine SCHEMBL8339 | 0.97 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDGLAACHE | |
| Acridine SCHEMBL29352289 | 0.97 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDGLAACHE | |
| Anthracene SCHEMBL9879830 | 0.94 | MAPT (0.94) | ALDH1A1MAPTHPGDGLAACHE | |
| Acridine SCHEMBL1551975 | 0.94 | ALDH1A1 (0.94) | ALDH1A1MAPTHPGDGLAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11579152-B2 | Engineered hERG channel proteins, vesicles and methods of identifying small molecule pharmacological agents | THE ROCKEFELLER UNIVERSITY (US) | 2023-02-14 | — | — | US | claimed |
| US-20210102956-A1 | ASSAY FOR hERG CHANNEL SENSITIVITY TO SMALL MOLECULE PHARMACOLOGICAL AGENTS | UNIV ROCKEFELLER (US) | 2021-04-08 | — | — | US | claimed |
| EP-3435955-A1 | ASSAY FOR hERG CHANNEL SENSITIVITY TO SMALL MOLECULE PHARMACOLOGICAL AGENTS | The Rockefeller University (US) | 2019-02-06 | — | — | EP | claimed |
| CN-104487446-B | The method for reducing aggregation content in protein formulation using the multi-functional surface of mixing | 新加坡科技研究局 | 2018-05-29 | — | — | CN | claimed |
| US-20170280984-A1 | POLYMER-TYPE FLUORESCENT MOLECULE PROBE | MAEDA HIROSHI (JP) | 2017-10-05 | — | — | US | claimed |
| WO-2017173257-A1 | ASSAY FOR hERG CHANNEL SENSITIVITY TO SMALL MOLECULE PHARMACOLOGICAL AGENTS | THE ROCKEFELLER UNIVERSITY (US) | 2017-10-05 | — | — | WO | claimed |
| CN-104487446-A | Methods for use of mixed multifunctional surfaces for reducing aggregate content in protein preparations | AGENCY SCIENCE TECH & RES | 2015-04-01 | — | — | CN | claimed |
| US-20140294735-A1 | POLYMER-TYPE FLUORESCENT MOLECULE PROBE | HIROSHI MAEDA (JP) | 2014-10-02 | — | — | US | claimed |
| EP-2774625-A1 | POLYMER-TYPE FLUORESCENT MOLECULE PROBE | Maeda, Hiroshi (JP) | 2014-09-10 | — | — | EP | claimed |
| US-11579152-B2 | Engineered hERG channel proteins, vesicles and methods of identifying small molecule pharmacological agents | THE ROCKEFELLER UNIVERSITY (US) | 2023-02-14 | — | — | US | disclosed |
| US-20210102956-A1 | ASSAY FOR hERG CHANNEL SENSITIVITY TO SMALL MOLECULE PHARMACOLOGICAL AGENTS | UNIV ROCKEFELLER (US) | 2021-04-08 | — | — | US | disclosed |
| US-10946109-B2 | Polymer-type fluorescent molecule probe | HIROSHI MAEDA (JP) | 2021-03-16 | — | — | US | disclosed |
| CN-105189530-B | The chromatogram purification antibody from shortage chromatinic cell culture harvest object | 新加坡科技研究局 | 2019-06-07 | — | — | CN | disclosed |
| CN-106752954-B | CCB high sealing water-repellent paint | 广东鼎新高新科技股份有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-104487446-A | Methods for use of mixed multifunctional surfaces for reducing aggregate content in protein preparations | AGENCY SCIENCE TECH & RES | 2015-04-01 | — | — | CN | disclosed |
| US-20140294735-A1 | POLYMER-TYPE FLUORESCENT MOLECULE PROBE | HIROSHI MAEDA (JP) | 2014-10-02 | — | — | US | disclosed |
| EP-2774625-A1 | POLYMER-TYPE FLUORESCENT MOLECULE PROBE | Maeda, Hiroshi (JP) | 2014-09-10 | — | — | EP | disclosed |
| WO-2005118580-A2 | TRICYCLIC COMPOUNDS AS INHIBITORS OF THE HYPOXIC SIGNALING PATHWAY | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH (US) | 2005-12-15 | — | — | WO | disclosed |
| EP-0649656-B1 | Pharmaceutical compositions based on acriflavine useful for the treatment of herpes and zona | RICHARD LAB M (FR) | 2001-08-16 | — | — | EP | disclosed |
| EP-0649656-A1 | Pharmaceutical compositions based on acriflavine useful for the treatment of herpes and zona | LABORATOIRE M. RICHARD (FR) | 1995-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140294735-A1 | POLYMER-TYPE FLUORESCENT MOLECULE PROBE | PBRM1, EPCAM, CD44 | ALDH1A1 1962/4885MAPT 1589/4885HPGD 2468/4885 |
| US-10946109-B2 | Polymer-type fluorescent molecule probe | MKI67, PBRM1, CD44 | ALDH1A1 1844/4885MAPT 1355/4885HPGD 2482/4885 |
| US-20170280984-A1 | POLYMER-TYPE FLUORESCENT MOLECULE PROBE | MKI67, PBRM1, CD44 | ALDH1A1 1844/4885MAPT 1355/4885HPGD 2482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.