Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.67 |
| ▸ | CACNA1C | Q13936 | 6/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.67 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.67 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11360822 | 0.95 | ADORA3 (0.62) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL6425245 | 0.94 | CACNA1D (0.61) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL11369478 | 0.93 | CYP1A2 (0.60) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL9689499 | 0.93 | ADORA3 (0.62) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL10647337 | 0.91 | CACNA1D (0.70) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL6427366 | 0.91 | CACNA1D (0.57) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL11165785 | 0.91 | CACNA1C (0.57) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL11117647 | 0.90 | CACNA1D (0.56) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL10646965 | 0.90 | CACNA1D (0.56) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 | |
| SCHEMBL10369519 | 0.90 | ADORA3 (0.58) | ADORA3CACNA1CCYP1A2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151989-B1 | MEANS FOR THE TREATMENT OF CARDIAC DISEASES | Ismail, Roshdy, Dr. (DE) | 1991-04-10 | — | — | EP | claimed |
| EP-0143857-B1 | THERAPEUTIC CORONARY COMPOSITION IN THE FORM OF SOFT GELATINE CAPSULES | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1988-04-06 | — | — | EP | claimed |
| EP-0143857-A1 | Therapeutic coronary composition in the form of soft gelatine capsules | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1985-06-12 | — | — | EP | claimed |
| EP-1345618-B1 | CHLORZOXAZONE FOR THE TREATMENT OF PSORIASIS | SWITCH BIOTECH AG (DE) | 2005-03-23 | — | — | EP | disclosed |
| EP-0868422-A1 | ULTRAMICROEMULSION OF SPONTANEOUSLY DISPERSIBLE CONCENTRATES OF ESTERS OF BACCATIN-III COMPOUNDS WITH ANTITUMOR AND ANTIVIRAL EFFECT | MARIGEN S.A. (CH) | 1998-10-07 | — | — | EP | disclosed |
| EP-0858331-A1 | SPONTANEOUSLY DISPERSIBLE CONCENTRATES OF STEROL ESTERS AND VITAMIN D DERIVATIVES WITH ANTIVIRAL, VIRUCIDAL AND/OR PARASITICIDAL EFFECT | MARIGEN S.A. (CH) | 1998-08-19 | — | — | EP | disclosed |
| WO-1998013359-A1 | ULTRAMICROEMULSION OF SPONTANEOUSLY DISPERSIBLE CONCENTRATES OF ESTERS OF BACCATIN-III COMPOUNDS WITH ANTITUMOR AND ANTIVIRAL EFFECT | MARIGEN S.A. (CH) | 1998-04-02 | — | — | WO | disclosed |
| WO-1998006390-A1 | SPONTANEOUSLY DISPERSIBLE CONCENTRATES OF STEROL ESTERS AND VITAMIN D DERIVATIVES WITH ANTIVIRAL, VIRUCIDAL AND/OR PARASITICIDAL EFFECT | MARIGEN S.A. (CH) | 1998-02-19 | — | — | WO | disclosed |
| US-5593691-A | DIESTERS AND UNSATURATED DIESTERS WITH COSMETICS, DRUGS AND TENSIDES | MARIGEN S.A. (CH) | 1997-01-14 | — | — | US | disclosed |
| EP-0078430-B2 | PROCESS FOR PREPARING SOLID FAST-RELEASING DRUG FORMULATIONS OF DIHYDROPYRIDINES | BAYER AG (DE) | 1993-02-10 | — | — | EP | disclosed |
| EP-0151989-B1 | MEANS FOR THE TREATMENT OF CARDIAC DISEASES | Ismail, Roshdy, Dr. (DE) | 1991-04-10 | — | — | EP | disclosed |
| EP-0143857-B1 | THERAPEUTIC CORONARY COMPOSITION IN THE FORM OF SOFT GELATINE CAPSULES | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1988-04-06 | — | — | EP | disclosed |
| EP-0078430-B1 | PROCESS FOR PREPARING SOLID FAST-RELEASING DRUG FORMULATIONS OF DIHYDROPYRIDINES | BAYER AG (DE) | 1986-04-23 | — | — | EP | disclosed |
| EP-0158955-A2 | Hexahydropyridines, process for their preparation and their use as pharmaceutical compounds | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |
| EP-0158956-A2 | 4-(Nitrophenyl)-tetrahydropyridines, process for their preparation and their application as pharmaceutical compounds | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |
| EP-0111455-A2 | Unsaturated lactones | CIBA-GEIGY AG (CH) | 1984-06-20 | — | — | EP | disclosed |
| EP-0078430-A2 | Process for preparing solid fast-releasing drug formulations of dihydropyridines | BAYER AG (DE) | 1983-05-11 | — | — | EP | disclosed |
| EP-0042093-A2 | 4-Aralkyl-1,4-dihydropyridines, processes for praparing them, their use as medicines and preparation thereof | BAYER AG (DE) | 1981-12-23 | — | — | EP | disclosed |
| EP-0042092-A2 | 1,4-Dihydropyridine-4-carboxamides, process for preparing them, their use as medicines and preparation thereof | BAYER AG (DE) | 1981-12-23 | — | — | EP | disclosed |
| EP-0042089-A2 | 4-Heterocylic substituted dihydropyridines, processes for preparing them, their therapeutical use and their preparation | BAYER AG (DE) | 1981-12-23 | — | — | EP | disclosed |