Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13319008 | 1.00 | KAT2B (0.46) | KAT2BMAPK1L3MBTL1TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11909173 | 0.99 | KAT2B (0.47) | KAT2BMAPK1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL13834721 | 0.82 | MEN1 (0.50) | ALDH1A1MAPTCYP3A4CYP2C9PRKCQ | |
| SCHEMBL13319009 | 0.81 | KAT2B (0.51) | KAT2BMAPK1L3MBTL1TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL13834520 | 0.81 | MEN1 (0.49) | ALDH1A1MAPTCYP3A4CYP2C9PRKCQ | |
| Hydrochloric Acid SCHEMBL6379 | 0.81 | BRD3 (0.43) | TDP1ALDH1A1MAPTCYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL6092 | 0.81 | CHRM3 (0.41) | MAPK1ALDH1A1MAPTPRKCQSMN1; SMN2 | |
| SCHEMBL23997424 | 0.80 | ALDH1A1 (0.51) | KAT2BMAPK1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL13834543 | 0.80 | NPC1 (0.49) | MAPTCYP3A4CYP2C9PRKCQNPC1 | |
| SCHEMBL2010060 | 0.80 | RPS6KB1 (0.41) | L3MBTL1ALDH1A1CYP3A4CYP2C9PRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493310-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GlaxoSmithKline LLC (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056635-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-05-12 | — | — | WO | disclosed |