SCHEMBL6428202

SCHEMBL6428202

CCCCCCCCCCCCCCCCCCc1ccc2c([nH]c3ccccc32)c1CCCCCCCCCCCCCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.52
MAPK1 P28482 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
KDM4E B2RXH2 4/20 0.52
HSD17B10 Q99714 4/20 0.52
ALDH1A1 P00352 3/20 0.52
HPGD P15428 3/20 0.52
GAA P10253 1/20 0.50
CTSV O60911 2/20 0.48
CTSL P07711 2/20 0.48
KIF11 P52732 2/20 0.45
RAB9A P51151 1/20 0.44
PARP14 Q460N5 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ATM Q13315 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
GABRP O00591 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23803147 1.00 MAPT (0.52) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL21753799 0.99 MAPT (0.54) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL4330629 0.94 MAPK1 (0.55) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL2548395 0.93 HSD17B10 (0.54) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL27985630 0.93 KDM4E (0.48) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL29025958 0.93 KDM4E (0.48) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL28767664 0.92 KDM4E (0.53) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL27912728 0.87 MAPK1 (0.50) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL28153486 0.85 MAPT (0.54) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL28728872 0.85 KDM4E (0.45) MAPTMAPK1NPSR1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6899983-B2 Electrophotographic photoconductor, electrophotographic apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2005-05-31 US disclosed
US-20040048177-A1 Electrophotographic photoconductor, electrophotographic apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2004-03-11 US disclosed