SCHEMBL21753799

SCHEMBL21753799

CCCCCc1ccc2c([nH]c3ccccc32)c1CCCCC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.54
MAPK1 P28482 2/20 0.54
NPSR1 Q6W5P4 2/20 0.54
KDM4E B2RXH2 8/20 0.51
HSD17B10 Q99714 5/20 0.51
ALDH1A1 P00352 5/20 0.51
HPGD P15428 5/20 0.51
GAA P10253 1/20 0.51
KIF11 P52732 2/20 0.46
CTSV O60911 1/20 0.46
CTSL P07711 1/20 0.46
RAB9A P51151 1/20 0.46
PARP14 Q460N5 1/20 0.43
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
TSHR P16473 2/20 0.43
GABRP O00591 3/20 0.43
GABRD O14764 3/20 0.43
GABRA1 P14867 3/20 0.43
GABRB1 P18505 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6428202 0.99 MAPT (0.52) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL23803147 0.99 MAPT (0.52) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL4330629 0.95 MAPK1 (0.55) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL29025958 0.92 KDM4E (0.48) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL27985630 0.92 KDM4E (0.48) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL2548395 0.92 HSD17B10 (0.54) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL28767664 0.90 KDM4E (0.53) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL27912728 0.88 MAPK1 (0.50) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL28153486 0.86 MAPT (0.54) MAPTMAPK1NPSR1KDM4EHSD17B10
SCHEMBL28020635 0.85 MAPT (0.50) MAPTMAPK1NPSR1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112110847-A Novel diarylacylcarbazole compound and application thereof as sensitizer 江苏英力科技发展有限公司 2020-12-22 CN claimed
US-11937495-B2 Organic light emitting element, composition and membrane KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2024-03-19 US disclosed
EP-3843168-B1 ORGANIC LIGHT EMITTING ELEMENT, COMPOSITION AND MEMBRANE UNIV KYUSHU NAT UNIV CORP (JP) 2023-10-11 EP disclosed
CN-113518774-A Novel diarylacylcarbazole compound and application thereof as sensitizer 艾坚蒙(安庆)科技发展有限公司 2021-10-19 CN disclosed
EP-3843168-A1 ORGANIC LIGHT EMITTING ELEMENT, COMPOSITION AND MEMBRANE Kyushu University, National University Corporation (JP) 2021-06-30 EP disclosed
CN-112585778-A Organic light-emitting element, composition, and film 国立大学法人九州大学 2021-03-30 CN disclosed
CN-112110848-A Novel diarylacylcarbazole compound and application thereof as sensitizer 江苏英力科技发展有限公司 2020-12-22 CN disclosed
CN-112110847-A Novel diarylacylcarbazole compound and application thereof as sensitizer 江苏英力科技发展有限公司 2020-12-22 CN disclosed
WO-2020039930-A1 ORGANIC LIGHT EMITTING ELEMENT, COMPOSITION AND MEMBRANE 国立大学法人九州大学 2020-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11937495-B2 Organic light emitting element, composition and membrane CRY1, INTS9, CYBA MAPT 3556/4885MAPK1 2913/4885NPSR1 4460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.