Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 11/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 2/20 | 0.35 |
| ▸ | STAT1 | P42224 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SDHB | P21912 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6304517 | 0.85 | GLP1R (0.56) | GLP1RSMN1; SMN2HPGDHSD17B10S1PR4 | |
| SCHEMBL6306402 | 0.72 | GLP1R (0.62) | GLP1R | |
| SCHEMBL6307056 | 0.72 | GLP1R (0.51) | GLP1RSMN1; SMN2HPGDHSD17B10LMNA | |
| SCHEMBL6306300 | 0.68 | GLP1R (1.00) | GLP1R | |
| SCHEMBL6307038 | 0.64 | GLP1R (0.52) | GLP1RLMNAKMT2AALDH1A1HTT | |
| SCHEMBL6312429 | 0.62 | GLP1R (0.47) | GLP1RHSD17B10S1PR1NPSR1KMT2A | |
| SCHEMBL6307183 | 0.62 | GLP1R (0.47) | GLP1RHSD17B10S1PR1NPSR1KMT2A | |
| SCHEMBL6310547 | 0.60 | GLP1R (0.64) | GLP1R | |
| SCHEMBL6303718 | 0.57 | GLP1R (0.53) | GLP1RHPGDLMNANPSR1KMT2A | |
| SCHEMBL6305874 | 0.57 | GLP1R (0.53) | GLP1RHPGDLMNANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |