Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 3/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.45 |
| ▸ | POLQ | O75417 | 8/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270115 | 0.71 | DAO (0.44) | EGLN1POLQDAOPSEN1PSEN2 | |
| SCHEMBL6306300 | 0.70 | GLP1R (1.00) | GLP1R | |
| SCHEMBL6306402 | 0.69 | GLP1R (0.62) | GLP1R | |
| SCHEMBL6307205 | 0.66 | GLP1R (0.70) | GLP1R | |
| SCHEMBL6304517 | 0.66 | GLP1R (0.56) | GLP1RKMT2ALMNAMAPTHTT | |
| SCHEMBL6428295 | 0.64 | GLP1R (0.50) | GLP1RKMT2AALDH1A1LMNAHTT | |
| SCHEMBL6306455 | 0.64 | GLP1R (0.61) | GLP1R | |
| SCHEMBL31589470 | 0.62 | POLQ (0.56) | POLQDAO | |
| SCHEMBL271989 | 0.62 | CES2 (0.43) | POLQDAOKMT2AALDH1A1FLT1 | |
| SCHEMBL2906179 | 0.62 | CES2 (0.47) | POLQFLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |