Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 7/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5843332 | 0.84 | S1PR4 (0.44) | CRHR1S1PR4NPC1LMNAMAPT | |
| SCHEMBL5844565 | 0.83 | CRHR1 (0.39) | CRHR1S1PR4MAPT | |
| SCHEMBL5844211 | 0.82 | CRHR1 (0.38) | CRHR1S1PR4MAPT | |
| SCHEMBL5844044 | 0.81 | CRHR1 (0.57) | CRHR1 | |
| SCHEMBL5845747 | 0.80 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL5843244 | 0.79 | CRHR1 (0.42) | CRHR1LMNAMAPT | |
| SCHEMBL5843013 | 0.78 | CRHR1 (0.50) | CRHR1NPC1MAPT | |
| SCHEMBL5845050 | 0.78 | CRHR1 (0.37) | CRHR1S1PR4TAS1R3TAS1R1LMNA | |
| SCHEMBL5843223 | 0.76 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL5843144 | 0.75 | CRHR1 (0.69) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844351-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-01-18 | — | — | US | disclosed |