Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893432 | 0.88 | PPARG (0.46) | PPARGPPARA | |
| SCHEMBL4896410 | 0.79 | PPARG (0.38) | PPARGPPARA | |
| SCHEMBL4894955 | 0.78 | PPARG (0.46) | PPARGPPARA | |
| SCHEMBL4893439 | 0.75 | PPARG (0.65) | PPARGPPARA | |
| SCHEMBL14154337 | 0.74 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL5512118 | 0.74 | PPARG (0.51) | PPARGPPARA | |
| SCHEMBL4890710 | 0.71 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL27607480 | 0.70 | RARA (0.43) | PPARGPPARA | |
| SCHEMBL5508411 | 0.69 | PPARG (0.51) | PPARGPPARA | |
| SCHEMBL4889260 | 0.69 | RARA (0.41) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050075378-A1 | Modulators of peroxisome proliferator activated receptors (ppar) | ELI LILLY AND COMPANY | 2005-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075378-A1 | Modulators of peroxisome proliferator activated receptors (ppar) | PPARG, PPARA, PPARD | PPARG 1/4885PPARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.