Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 13/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27984977 | 0.82 | NOTUM (0.43) | NOTUMKEAP1CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL18378736 | 0.82 | NOTUM (0.47) | NOTUMTSHRKEAP1ALDH1A1CYP1A2 | |
| SCHEMBL454021 | 0.82 | GAA (0.47) | NOTUMKEAP1CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL3387244 | 0.79 | NOTUM (0.53) | NOTUMTSHRKEAP1ALDH1A1CYP1A2 | |
| SCHEMBL27613715 | 0.79 | NOTUM (0.44) | NOTUMKEAP1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL22702085 | 0.79 | NOTUM (0.47) | NOTUMKEAP1CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL15774805 | 0.79 | NOTUM (0.45) | NOTUMKEAP1CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL7111602 | 0.79 | NOTUM (0.44) | NOTUMKEAP1CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL21376045 | 0.79 | NOTUM (0.49) | NOTUMKEAP1CYP1A2CYP2C9CHRNB2 | |
| SCHEMBL17194959 | 0.77 | MAPK1 (0.50) | NOTUMCYP3A4TSHRPIK3CAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | NOTUM 607/4885CYP3A4 25/4885TSHR 3470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.