Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6427068 | 1.00 | DRD3 (0.41) | DRD3PTK2DYRK1AMAPK1OPRK1 | |
| SCHEMBL6425838 | 0.95 | DRD3 (0.44) | DRD3PTK2DYRK1AHTR4LMNA | |
| SCHEMBL4152746 | 0.91 | DRD3 (0.47) | DRD3DYRK1ALMNANTRK1CNR1 | |
| SCHEMBL4152742 | 0.91 | DRD3 (0.47) | DRD3DYRK1ALMNANTRK1CNR1 | |
| SCHEMBL4141124 | 0.89 | DRD3 (0.46) | DRD3DYRK1ALMNACNR1CNR2 | |
| SCHEMBL4145954 | 0.89 | CNR1 (0.46) | DRD3DYRK1ALMNACNR1CNR2 | |
| SCHEMBL4141120 | 0.89 | DRD3 (0.46) | DRD3DYRK1ALMNACNR1CNR2 | |
| SCHEMBL4145950 | 0.89 | CNR1 (0.46) | DRD3DYRK1ALMNACNR1CNR2 | |
| SCHEMBL6426406 | 0.87 | DRD3 (0.44) | DRD3DYRK1ALMNANTRK1CNR1 | |
| SCHEMBL6427314 | 0.84 | HTR4 (0.44) | PTK2HTR4HDAC4HDAC6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261339-A1 | Pyrazole compound and medicinal composition containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261339-A1 | Pyrazole compound and medicinal composition containing the same | CNKSR1, NR3C2, CSNK2B | DRD3 1224/4885PTK2 348/4885DYRK1A 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.