Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.71 |
| ▸ | GSK3A | P49840 | 6/20 | 0.71 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.71 |
| ▸ | CDK1 | P06493 | 1/20 | 0.71 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.71 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.71 |
| ▸ | RGS4 | P49798 | 11/20 | 0.49 |
| ▸ | RGS8 | P57771 | 10/20 | 0.49 |
| ▸ | PRKCA | P17252 | 2/20 | 0.46 |
| ▸ | RGS16 | O15492 | 1/20 | 0.43 |
| ▸ | RGS19 | P49795 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023669 | 0.85 | GSK3A (0.73) | GSK3BGSK3ACCNB2CDK1CCNB1 | |
| SCHEMBL5023665 | 0.85 | GSK3B (0.73) | GSK3BGSK3ACCNB2CDK1CCNB1 | |
| SCHEMBL18802339 | 0.83 | GSK3B (0.71) | GSK3BGSK3ACCNB2CDK1CCNB1 | |
| SCHEMBL139834 | 0.83 | GSK3B (1.00) | GSK3BGSK3ACCNB2CDK1CCNB1 | |
| SCHEMBL29210526 | 0.81 | RGS4 (0.73) | GSK3BGSK3ACCNB2CDK1CCNB1 | |
| SCHEMBL5023670 | 0.81 | GSK3A (0.67) | GSK3BGSK3ACCNB2CDK1CCNB1 | |
| SCHEMBL29210473 | 0.80 | GSK3B (0.54) | GSK3BGSK3ACCNB2CDK1CCNB1 | |
| SCHEMBL6427057 | 0.80 | GSK3A (0.65) | GSK3BGSK3ACCNB2CDK1CCNB1 | |
| SCHEMBL18809907 | 0.72 | HDAC3 (0.54) | GSK3BGSK3ACCNB2CDK1CCNB1 | |
| SCHEMBL18810124 | 0.70 | GSK3A (0.52) | GSK3BGSK3ACCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005024755-A2 | MEDICAMENTS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS OR DIABETES | DECIPHERA PHARMACEUTICALS, LLC. (US) | 2005-03-17 | — | — | WO | disclosed |