Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123966 | 0.81 | DHODH (0.72) | DHODHMEN1KMT2ATP53HTT | |
| SCHEMBL6430181 | 0.81 | DHODH (0.61) | DHODHMEN1KMT2ATP53HTT | |
| SCHEMBL1124252 | 0.75 | DHODH (1.00) | DHODHMEN1KMT2AHTTMAPT | |
| SCHEMBL6246502 | 0.71 | DHODH (0.52) | DHODHTP53 | |
| SCHEMBL518904 | 0.71 | DHODH (0.71) | DHODH | |
| SCHEMBL1124246 | 0.71 | DHODH (1.00) | DHODHMEN1KMT2AMAPTNPC1 | |
| SCHEMBL517803 | 0.71 | DHODH (0.74) | DHODH | |
| SCHEMBL6430362 | 0.71 | DHODH (0.58) | DHODHMEN1KMT2ATP53HTT | |
| SCHEMBL15902456 | 0.70 | DHODH (0.81) | DHODHMEN1KMT2ATP53HTT | |
| SCHEMBL1337628 | 0.70 | AKR1C2 (0.55) | DHODHMEN1KMT2ATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578741-A1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004056797-A1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2004-07-08 | — | — | WO | disclosed |