Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 11/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430181 | 0.90 | DHODH (0.61) | DHODHKMT2AMEN1TP53HTT | |
| SCHEMBL1123967 | 0.81 | DHODH (0.68) | DHODHKMT2AMEN1 | |
| SCHEMBL1124081 | 0.80 | DHODH (0.73) | DHODHKMT2AMEN1HTT | |
| SCHEMBL16485603 | 0.77 | DHODH (0.60) | DHODHKMT2A | |
| SCHEMBL6447571 | 0.77 | DHODH (0.55) | DHODHKMT2AMEN1ANO1 | |
| SCHEMBL1124423 | 0.74 | DHODH (1.00) | DHODHKMT2AHTTMAPT | |
| SCHEMBL18118633 | 0.72 | DHODH (0.81) | DHODH | |
| SCHEMBL6429467 | 0.71 | DHODH (0.60) | DHODHKMT2AMEN1ACLYTP53 | |
| SCHEMBL517805 | 0.70 | DHODH (1.00) | DHODH | |
| SCHEMBL30511209 | 0.70 | DHODH (0.77) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578741-A1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004056797-A1 | AROMATIC COMPOUNDS AS ANTI-INFLAMMATORY, IMMUNOMODULATORY AND ANTI-PROLIFERATORY AGENTS | 4SC AG (DE) | 2004-07-08 | — | — | WO | disclosed |