Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 8/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 8/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 8/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30011106 | 1.00 | SLC7A5 (0.40) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL7689414 | 0.84 | SLC7A5 (0.43) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL5668511 | 0.75 | SLC7A5 (0.46) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27517173 | 0.75 | SLC7A5 (0.46) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27517174 | 0.75 | SLC7A5 (0.46) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27560399 | 0.73 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27547547 | 0.73 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3930054 | 0.69 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL31376432 | 0.69 | — | — | |
| SCHEMBL8003127 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001764-A4 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO INC (US) | 2005-08-24 | — | — | EP | claimed |
| JP-2002512625-A | — | — | 2002-04-23 | — | — | JP | claimed |
| EP-1001764-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | Merck & Co., Inc. (a New Jersey corp.) (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999064395-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1999-12-16 | — | — | WO | claimed |
| WO-1998053814-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1998-12-03 | — | — | WO | claimed |