Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 11/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 11/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 11/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429649 | 0.84 | SLC7A5 (0.40) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL30011106 | 0.84 | SLC7A5 (0.40) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL27517173 | 0.79 | SLC7A5 (0.46) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27517174 | 0.79 | SLC7A5 (0.46) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5668511 | 0.79 | SLC7A5 (0.46) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL60300 | 0.78 | ALDH1A1 (0.35) | MEN1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL27560399 | 0.77 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27547547 | 0.77 | SLC7A5 (0.56) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4953782 | 0.76 | SLC7A5 (0.42) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL4950087 | 0.76 | SLC7A5 (0.42) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115477683-A | Dioxiexacyclo-tetrahydrocarboline-3-formylamino acid with interleukin-6 as target and preparation and application thereof | 首都医科大学 | 2022-12-16 | — | — | CN | disclosed |
| US-6437145-B1 | REACTING N-PROTECTED AMINODICARBOXYLIC ACIDS WITH A DEHYDRATING AGENT TO FORM CYCLIC ANHYDRIDES WHICH ARE REACTED WITH CARBONYL COMPOUNDS; FOR THE ALPHA-SELECTIVE PRODUCTION OF ESTERS OR AMIDES OF DICARBOXYLIC AMINO ACIDS | DEGUSSA-HULS AG (DE) | 2002-08-20 | — | — | US | disclosed |
| US-6051715-A | Method of producing oxazolidinones, the use thereof and novel oxazolidinones | DEGUSSA-HULS AG (DE) | 2000-04-18 | — | — | US | disclosed |