Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.68 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | CD40 | P25942 | 1/20 | 0.42 |
| ▸ | CD40LG | P29965 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6078681 | 0.98 | PRMT1 (0.64) | PRMT1SIRT1CASP6CTDSP1NT5E | |
| SCHEMBL6427772 | 0.84 | IDH1 (0.48) | PRMT1IDH1 | |
| SCHEMBL6078800 | 0.84 | PRMT1 (0.74) | PRMT1SIRT1CASP6CTDSP1NT5E | |
| SCHEMBL10823628 | 0.84 | PRMT1 (0.78) | PRMT1SIRT1CASP6CTDSP1NT5E | |
| SCHEMBL6078726 | 0.83 | PRMT1 (0.72) | PRMT1SIRT1CASP6CTDSP1NT5E | |
| SCHEMBL6079153 | 0.83 | PRMT1 (0.72) | PRMT1SIRT1CASP6CTDSP1NT5E | |
| SCHEMBL10823776 | 0.83 | PRMT1 (0.71) | PRMT1SIRT1CASP6CTDSP1IDH1 | |
| SCHEMBL6079555 | 0.83 | PRMT1 (0.57) | PRMT1SIRT1 | |
| SCHEMBL2679101 | 0.82 | PRMT1 (1.00) | PRMT1SIRT1CASP6CTDSP1NT5E | |
| SCHEMBL29349608 | 0.82 | PRMT1 (1.00) | PRMT1SIRT1CASP6CTDSP1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181271-B1 | NAPHTHALENE UREAS AS GLUCOSE UPTAKE ENHANCERS | TELIK INC (US) | 2005-01-19 | — | — | EP | disclosed |