Sugi Predict

Sugi Predict / Compounds / SCHEMBL6427772

SCHEMBL6427772

SCHEMBL6427772

O=C(Nc1ccc2ccc(S(=O)(=O)O)cc2c1)Nc1ccc2ccc(S(=O)(=O)Nc3ccc(Cl)c(S(=O)(=O)O)c3)cc2c1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ IDH1 O75874 5/20 0.48
▸ PRMT1 Q99873 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6078456 0.98 IDH1 (0.50) IDH1
SCHEMBL29398619 0.98 IDH1 (0.50) IDH1
SCHEMBL6428822 0.85 PRMT1 (0.56) IDH1PRMT1
SCHEMBL6429672 0.84 PRMT1 (0.68) IDH1PRMT1
SCHEMBL6078681 0.84 PRMT1 (0.64) IDH1PRMT1
SCHEMBL6078234 0.84 PRMT1 (0.54) IDH1PRMT1
SCHEMBL6078878 0.83 MEN1 (0.55) IDH1PRMT1
SCHEMBL6079569 0.83 MEN1 (0.55) IDH1PRMT1
SCHEMBL6078621 0.83 MEN1 (0.55) IDH1PRMT1
SCHEMBL6079410 0.83 MEN1 (0.55) IDH1PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1181271-B1 NAPHTHALENE UREAS AS GLUCOSE UPTAKE ENHANCERS TELIK INC (US) 2005-01-19 — — EP disclosed