Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5843507 | 0.80 | CRHR1 (0.76) | CRHR1 | |
| SCHEMBL5844155 | 0.77 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL29482253 | 0.66 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL3226278 | 0.66 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL5844439 | 0.65 | CRHR1 (0.78) | CRHR1 | |
| SCHEMBL6393855 | 0.65 | CRHR1 (0.63) | CRHR1 | |
| SCHEMBL25561433 | 0.65 | TSHR (0.37) | CRHR1 | |
| SCHEMBL16606728 | 0.65 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL5845766 | 0.64 | CRHR1 (0.61) | CRHR1 | |
| SCHEMBL5845769 | 0.64 | CRHR1 (0.61) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6956047-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-10-18 | — | — | US | disclosed |