Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430080 | 0.96 | CYP2C19 (0.36) | CYP2C19HIF1ATAAR1LMNA | |
| SCHEMBL5526988 | 0.94 | CYP2C19 (0.41) | CYP2C19HIF1ATAAR1LMNA | |
| SCHEMBL5518734 | 0.89 | CYP2C19 (0.40) | CYP2C19HIF1ATAAR1LMNA | |
| SCHEMBL6505272 | 0.88 | CYP2C19 (0.39) | CYP2C19HIF1ATAAR1LMNA | |
| SCHEMBL6693262 | 0.83 | CYP2C19 (0.40) | CYP2C19HIF1A | |
| SCHEMBL6506245 | 0.83 | CYP2C19 (0.40) | CYP2C19HIF1ATAAR1LMNA | |
| SCHEMBL6708666 | 0.83 | CYP2C19 (0.40) | CYP2C19HIF1ATAAR1LMNA | |
| SCHEMBL6531583 | 0.81 | RIPK1 (0.33) | CYP2C19HIF1ATAAR1 | |
| SCHEMBL6698317 | 0.80 | CYP2C19 (0.39) | CYP2C19HIF1A | |
| SCHEMBL10264390 | 0.79 | CYP2C19 (0.39) | CYP2C19HIF1ATAAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539127-A1 | METHOD OF TREATING OSTEOARTHRITIS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004017952-A1 | METHOD OF TREATING OSTEOARTHRITIS | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |