Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 7/20 | 0.39 |
| ▸ | CDK8 | P49336 | 7/20 | 0.39 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429770 | 1.00 | HTR2A (0.42) | HTR2AKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL6429773 | 0.94 | HTR2A (0.42) | HTR2AKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL6438698 | 0.89 | HTR2A (0.43) | HTR2AKMT2AMEN1CYP3A4CYP2D6 | |
| SCHEMBL6438693 | 0.89 | HTR2A (0.43) | HTR2AKMT2AMEN1CYP3A4CYP2D6 | |
| SCHEMBL6429433 | 0.89 | CCNC (0.45) | KMT2AMEN1ALDH1A1CCNCCDK8 | |
| SCHEMBL6429439 | 0.89 | CCNC (0.45) | KMT2AMEN1ALDH1A1CCNCCDK8 | |
| SCHEMBL6434504 | 0.84 | CCNC (0.42) | HTR2AHTR2CMMP1MMP2MMP9 | |
| SCHEMBL6431330 | 0.84 | HDAC1 (0.41) | HTR2AKMT2AMEN1HTR2CCCNC | |
| SCHEMBL6434499 | 0.84 | CCNC (0.42) | HTR2AHTR2CMMP1MMP2MMP9 | |
| SCHEMBL6431320 | 0.84 | HDAC1 (0.41) | HTR2AKMT2AMEN1HTR2CCCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556032-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | Takeda Pharmaceutical Company Limited (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039365-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-13 | — | — | WO | disclosed |