SCHEMBL6429987

SCHEMBL6429987

CCCC(CC1(C(=O)Nc2cccnc2)CCCC1)C(=O)OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MME P08473 17/20 0.52
NAMPT P43490 1/20 0.46
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7452043 0.92 MME (0.48) MMENAMPTMEN1KMT2A
SCHEMBL7171776 0.86 MME (0.67) MME
SCHEMBL7452596 0.81 MME (0.59) MME
SCHEMBL6430188 0.80 MME (0.52) MME
SCHEMBL9337016 0.80 MME (0.52) MME
SCHEMBL7448045 0.78 MME (0.47) MME
SCHEMBL6429465 0.78 MME (0.50) MME
SCHEMBL7446023 0.76 MME (0.68) MME
SCHEMBL6938274 0.75 MME (0.57) MME
SCHEMBL6938276 0.75 MME (0.57) MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050070499-A1 Compounds for the treatment of female sexual dysfunction PFIZER INC. 2005-03-31 US disclosed
US-20050020547-A1 Compounds for the treatment of female sexual dysfunction PFIZER INC. 2005-01-27 US disclosed
EP-1097719-B1 NEP inhibitors for the treatment of female sexual dysfunction PFIZER LTD (GB) 2004-12-22 EP disclosed
US-20040254153-A1 Compounds for the treatment of female sexual dysfunction PFIZER INC 2004-12-16 US disclosed
EP-1481667-A1 NEP inhibitors for the treatment of female sexual dysfunction Pfizer Limited (GB) 2004-12-01 EP disclosed
US-6734186-B1 PHOSPHODIESTERASE 2 INHIBITOR PFIZER INC. 2004-05-11 US disclosed
EP-1097707-A1 Treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed
EP-1097718-A1 NPY antagonists for the treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed
EP-1097706-A1 Phosphodiesterase inhibitors for the treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040254153-A1 Compounds for the treatment of female sexual dysfunction FSHR, SHBG, PDE3A MME 2886/4885NAMPT 1675/4885MEN1 2032/4885
US-20050020547-A1 Compounds for the treatment of female sexual dysfunction FSHR, SHBG, PDE3A MME 2886/4885NAMPT 1675/4885MEN1 2032/4885
US-20050070499-A1 Compounds for the treatment of female sexual dysfunction FSHR, SHBG, PDE3A MME 2886/4885NAMPT 1675/4885MEN1 2032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.