⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1047030 | 0.72 | — | — | |
| SCHEMBL15384248 | 0.69 | — | — | |
| SCHEMBL88928 | 0.69 | — | — | |
| SCHEMBL11498913 | 0.69 | — | — | |
| SCHEMBL8089210 | 0.67 | — | — | |
| SCHEMBL11876113 | 0.67 | — | — | |
| SCHEMBL525827 | 0.67 | — | — | |
| SCHEMBL7034467 | 0.67 | ALDH1A1 (0.35) | — | |
| SCHEMBL1836645 | 0.67 | — | — | |
| SCHEMBL1231128 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826761-A1 | Use of polyhydroxycarboxylic acid amides as EP-additives | Schill & Seilacher GmbH & Co. (DE) | 1998-03-04 | — | — | EP | claimed |
| US-6875785-B2 | Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors | PHARMACIA CORPORATION (US) | 2005-04-05 | — | — | US | disclosed |
| US-20040248943-A9 | Pyrazole substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors | PHARMACIA CORPORATION | 2004-12-09 | — | — | US | disclosed |
| US-6753344-B2 | SULFONYL OR SULFONAMIDE SUBSTITUTED BENZENE DERIVATIVE CONTAINING HYDROXYUREA GROUP; USEFUL AS ANTIINFLAMMATORY AGENT | PHARMACIA CORPORATION | 2004-06-22 | — | — | US | disclosed |
| US-6696477-B2 | AS ANTIINFLAMMATORY AGENTS | PHARMACIA CORPORATION | 2004-02-24 | — | — | US | disclosed |
| US-20030176708-A1 | Thiophene substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors | PHARMACIA CORPORATION | 2003-09-18 | — | — | US | disclosed |
| US-20030119886-A1 | Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors | PHARMACIA CORPORATION | 2003-06-26 | — | — | US | disclosed |
| US-20030073722-A1 | Pyrazole substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors | PHARMACIA CORPORATION | 2003-04-17 | — | — | US | disclosed |
| EP-0709378-B1 | Aminoalkyloximes, a process for their preparation, their use as medicaments and intermediate compounds | AVENTIS PHARMA INC (US) | 2003-03-19 | — | — | EP | disclosed |
| US-6515014-B2 | Aminosulfonyl- or alkylsulfonylphenyl-heterocyclylalkylhydroxyamic acid or hydroxyurea derivatives; treating asthma and arthritis | G. D. SEARLE & CO. | 2003-02-04 | — | — | US | disclosed |
| US-5667949-A | PHOTOGRAPHIC FILM SUPPORTS WITH SILVER HALIDE EMULSIONS WITH STABILIZERS AND DEVELOPMENT WITH BROMIDE IONS | EASTMAN KODAK COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| US-5665756-A | Aminoalkyloximes useful in the treatment of depression and obsessive compulsive disorders | HOECHST MARION ROUSSEL, INC. (US) | 1997-09-09 | — | — | US | disclosed |
| US-5648367-A | ANTIDEPRESANTS, OBSESSIVE-COMPULSIVE DISORDER | HOECHST MARION ROUSSEL, INC. (US) | 1997-07-15 | — | — | US | disclosed |
| WO-1996038418-A1 | HETEROCYCLO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS CYCLOOXYGENASE-2 AND 5-LIPOXYGENASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-12-05 | — | — | WO | disclosed |
| EP-0724190-A2 | Method of processing originating photographic elements containing tabular grain emulsions | EASTMAN KODAK COMPANY (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0709378-A2 | Aminoalkyloximes, a process for their preparation, their use as medicaments and intermediate compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0289273-B1 | Light-sensitive silver halide photographic material | KONISHIROKU PHOTO IND (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-4997752-A | Mold resistance, bacteria resistance | KONICA CORPORATION (JP) | 1991-03-05 | — | — | US | disclosed |
| US-4272613-A | DYE DEVELOPER OF A PRIMARY AMINE, DISULFIDE OR DI(MERCAPTAN) AND PYRAZOLIDONE | FUJI PHOTO FILM CO., LTD. (JP) | 1981-06-09 | — | — | US | disclosed |
| US-4155763-A | DEVELOPER SOLUTION CONTAINS AROMATIC PRIMARY AMINE, N,N-DIETHYLHYDROXYLAMINE, AND A 1-ARYL-3-PYRAZOLIDONE CONTAINING TWO SUBSTITUENTS AT THE 4-POSITION | FUJI PHOTO FILM CO., LTD. (JP) | 1979-05-22 | — | — | US | disclosed |