Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762824 | 0.94 | ALOX5 (0.46) | ALOX5PTGS1PTGS2MAOBMAOA | |
| SCHEMBL23458034 | 0.85 | MAOB (0.54) | ALOX5MAOBTDP1NPC1ALDH1A1 | |
| SCHEMBL23457953 | 0.85 | MAOB (0.54) | ALOX5MAOBTDP1NPC1ALDH1A1 | |
| SCHEMBL23457959 | 0.82 | MAOB (0.58) | ALOX5PTGS1PTGS2MAOBMAOA | |
| SCHEMBL23457960 | 0.82 | MAOB (0.58) | ALOX5PTGS1PTGS2MAOBMAOA | |
| SCHEMBL7593174 | 0.80 | MAOB (0.61) | ALOX5PTGS1PTGS2MAOBMAOA | |
| SCHEMBL7593172 | 0.80 | MAOB (0.61) | ALOX5PTGS1PTGS2MAOBMAOA | |
| SCHEMBL23458000 | 0.80 | MAOB (0.61) | ALOX5PTGS1PTGS2MAOBMAOA | |
| SCHEMBL23458229 | 0.78 | MAOB (0.52) | ALOX5MAOBTDP1NPC1ALDH1A1 | |
| SCHEMBL243079 | 0.78 | MAOB (0.52) | ALOX5MAOBTDP1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474476-A4 | ENGINEERED POLYOLEFIN MATERIALS WITH ENHANCED SURFACE DURABILITY AND METHODS OF MAKING SAME | SOLVAY ENGINEERED POLYMERS (US) | 2005-03-23 | — | — | EP | disclosed |
| EP-1474476-A1 | ENGINEERED POLYOLEFIN MATERIALS WITH ENHANCED SURFACE DURABILITY AND METHODS OF MAKING SAME | Solvay Engineered Polymers (US) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068858-A1 | ENGINEERED POLYOLEFIN MATERIALS WITH ENHANCED SURFACE DURABILITY AND METHODS OF MAKING SAME | SOLVAY ENGINEERED POLYMERS (US) | 2003-08-21 | — | — | WO | disclosed |