Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6070767 | 0.88 | ADORA2A (0.44) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5386609 | 0.82 | SLC29A1 (0.54) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL24021943 | 0.79 | SLC29A1 (0.65) | SLC29A1ADORA3ADORA2AADORA1 | |
| SCHEMBL20419262 | 0.77 | SLC29A1 (0.62) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL23982263 | 0.77 | ADORA3 (0.67) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7737742 | 0.77 | ADORA3 (0.67) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7737737 | 0.77 | ADORA3 (0.67) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL11213486 | 0.75 | SLC29A1 (0.69) | SLC29A1ADORA3ADORA2AADORA1 | |
| SCHEMBL4977865 | 0.75 | SLC29A1 (0.60) | SLC29A1ADORA3 | |
| SCHEMBL11038083 | 0.75 | SLC29A1 (0.69) | SLC29A1ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590359-A2 | PARTIAL AND FULL AGONISTS OF A sb 1 /sb ADENOSINE RECEPTORS | CV Therapeutics Inc. (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004069185-A2 | PARTIAL AND FULL AGONISTS OF A1 ADENOSINE RECEPTORS | CV THERAPEUTICS INC. (US) | 2004-08-19 | — | — | WO | disclosed |