⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22533638 | 0.89 | FFAR3 (0.38) | — | |
| SCHEMBL2090673 | 0.89 | FFAR3 (0.38) | — | |
| SCHEMBL2089260 | 0.87 | CYP2C19 (0.38) | — | |
| Hydrochloric Acid SCHEMBL6601346 | 0.87 | FFAR3 (0.36) | — | |
| SCHEMBL17144836 | 0.83 | OPRM1 (0.39) | — | |
| SCHEMBL18125951 | 0.79 | OPRM1 (0.33) | — | |
| SCHEMBL23182667 | 0.78 | USP2 (0.45) | — | |
| SCHEMBL9781693 | 0.76 | OPRM1 (0.42) | — | |
| SCHEMBL27991065 | 0.76 | FFAR3 (0.36) | — | |
| SCHEMBL2843811 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116769253-B | Geogrid modified polypropylene engineering plastic and preparation method and application thereof | 山东路德新材料股份有限公司 | 2023-12-12 | — | — | CN | claimed |
| CN-117024878-A | Modified polypropylene geogrid raw material and geogrid | 山东路德新材料股份有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-116769253-A | Geogrid modified polypropylene engineering plastic and preparation method and application thereof | 山东路德新材料股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| US-12421249-B2 | Inhibitors of APOL1 and methods of using same | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-09-23 | — | — | US | disclosed |
| US-20240368180-A1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMACEUTICALS INCORPORATED | 2024-11-07 | — | — | US | disclosed |
| US-20240254140-A1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2024-08-01 | — | — | US | disclosed |
| EP-4405352-A1 | NEW COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | F. Hoffmann-La Roche AG (CH) | 2024-07-31 | — | — | EP | disclosed |
| CN-117980303-A | Novel compounds and their use in the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-11866446-B2 | Inhibitors of APOL1 and methods of using same | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-01-09 | — | — | US | disclosed |
| CN-116769253-B | Geogrid modified polypropylene engineering plastic and preparation method and application thereof | 山东路德新材料股份有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-117024878-A | Modified polypropylene geogrid raw material and geogrid | 山东路德新材料股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| US-7629339-B2 | inhibitors of protein kinases and are useful in treating cancer; 4-({5-[5-Fluoro-2-oxo-1,2-dihydro-indol-(3Z)-ylidenemethyl]-2,4-dimethyl-1H-pyrrole-3-carbonyl}-amino)-3-methoxy-butyric acid; anticarcinogenic agent | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-12-08 | — | — | US | disclosed |
| WO-2009144494-A1 | PHENOXYPYRIDINYLAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF PDE4 MEDIATED DISEASE STATES | ASTRAZENECA AB (SE) | 2009-12-03 | — | — | WO | disclosed |
| EP-2106396-A2 | CHEMICAL COMPOUNDS 637: PYRIDOPYRIMIDINEDIONES AS PDE4 INHIBITORS | AstraZeneca AB (SE) | 2009-10-07 | — | — | EP | disclosed |
| WO-2009068214-A2 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-04 | — | — | WO | disclosed |
| US-20090124596-A1 | Chemical Compounds 637 | ALCON RESEARCH, LTD. | 2009-05-14 | — | — | US | disclosed |
| WO-2008084223-A2 | CHEMICAL COMPOUNDS 637: PYRIDOPYRIMIDINEDIONES AS PDE4 INHIBITORS | ASTRAZENECA AB (SE) | 2008-07-17 | — | — | WO | disclosed |
| US-20080044881-A1 | Advanced Indolinone Based Protein Kinase Inhibitors | SCRIPPS RESEARCH INSTITUTE, THE | 2008-02-21 | — | — | US | disclosed |
| US-20070072934-A1 | Alkoxy indolinone based protein kinase inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-03-29 | — | — | US | disclosed |
| US-20070072934-A1 | Alkoxy indolinone based protein kinase inhibitors | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-03-29 | — | — | US | disclosed |