Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 19/20 | 0.73 |
| ▸ | HCRTR1 | O43613 | 14/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2133572 | 0.84 | HCRTR2 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL2025125 | 0.81 | HCRTR2 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL2131676 | 0.79 | HCRTR2 (0.72) | HCRTR2HCRTR1 | |
| SCHEMBL9949024 | 0.79 | HCRTR2 (0.91) | HCRTR2HCRTR1 | |
| SCHEMBL9949185 | 0.76 | HCRTR2 (0.78) | HCRTR2HCRTR1 | |
| SCHEMBL9948821 | 0.76 | HCRTR2 (0.66) | HCRTR2HCRTR1 | |
| SCHEMBL6423359 | 0.76 | HCRTR2 (0.64) | HCRTR2HCRTR1 | |
| SCHEMBL6422976 | 0.76 | HCRTR2 (0.44) | HCRTR2HCRTR1 | |
| SCHEMBL12641223 | 0.74 | HCRTR2 (0.63) | HCRTR2HCRTR1 | |
| SCHEMBL9948770 | 0.74 | HCRTR2 (0.79) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012055888-A1 | DIAZA-SPIRO[5.5]UNDECANES USEFUL AS OREXIN RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2012-05-03 | — | — | WO | disclosed |