Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 16/20 | 0.64 |
| ▸ | HCRTR1 | O43613 | 12/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2130959 | 0.80 | HCRTR2 (0.71) | HCRTR2HCRTR1 | |
| SCHEMBL2026883 | 0.78 | HCRTR2 (1.00) | HCRTR2HCRTR1 | |
| SCHEMBL6430669 | 0.76 | HCRTR2 (0.73) | HCRTR2HCRTR1 | |
| SCHEMBL12641223 | 0.76 | HCRTR2 (0.63) | HCRTR2HCRTR1 | |
| SCHEMBL6422976 | 0.76 | HCRTR2 (0.44) | HCRTR2HCRTR1 | |
| Hydrochloric Acid SCHEMBL2022807 | 0.75 | HCRTR2 (0.62) | HCRTR2HCRTR1 | |
| SCHEMBL12641233 | 0.75 | MEN1 (0.64) | HCRTR2HCRTR1MEN1KMT2AALDH1A1 | |
| SCHEMBL2026638 | 0.73 | HCRTR2 (0.63) | HCRTR2HCRTR1 | |
| SCHEMBL32667418 | 0.73 | LMNA (0.51) | HCRTR2HCRTR1OPRM1OPRD1MAPT | |
| SCHEMBL2025002 | 0.72 | HCRTR2 (0.70) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012055888-A1 | DIAZA-SPIRO[5.5]UNDECANES USEFUL AS OREXIN RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2012-05-03 | — | — | WO | disclosed |