SCHEMBL6430764

SCHEMBL6430764

COC(=O)c1cc(Oc2ccc(S(=O)(=O)O)cc2)cc(C(=O)OC)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.49
CYP2C9 P11712 3/20 0.46
KDM4E B2RXH2 1/20 0.45
KMT2A Q03164 1/20 0.44
STS P08842 1/20 0.44
TCF4 P15884 1/20 0.44
CTNNB1 P35222 1/20 0.44
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
ALDH1A1 P00352 4/20 0.43
CA12 O43570 2/20 0.43
CA9 Q16790 2/20 0.43
CA14 Q9ULX7 2/20 0.43
TSHR P16473 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
GLA P06280 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
LMNA P02545 2/20 0.42
HTT P42858 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472700 1.00 USP2 (0.49) USP2CYP2C9KDM4EKMT2ASTS
SCHEMBL472699 0.86 USP2 (0.48) USP2CYP2C9KDM4EKMT2ASTS
SCHEMBL1107748 0.84 GCK (0.50) USP2CYP2C9
SCHEMBL14612821 0.84 MAPT (0.53) KMT2ASTSALDH1A1TSHRSMN1; SMN2
SCHEMBL12742979 0.82 PTGS2 (0.46) USP2CYP2C9KDM4EALDH1A1SMN1; SMN2
SCHEMBL2668846 0.82 PTGS2 (0.49) USP2CYP2C9KMT2AALDH1A1POLB
SCHEMBL472613 0.82 LCK (0.58) KDM4EKMT2AALDH1A1TSHRSMN1; SMN2
SCHEMBL78937 0.82 LCK (0.58) KDM4EKMT2AALDH1A1TSHRSMN1; SMN2
SCHEMBL8984026 0.81 USP2 (0.53) USP2CYP2C9KDM4EKMT2ATCF4
SCHEMBL270676 0.81 CA12 (0.57) KDM4ECA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1203119-B1 INCREASING THE WET SLIPPAGE PROPERTIES OF TEXTILE MATERIAL CLARIANT FINANCE BVI LTD (VG) 2005-09-28 EP disclosed
EP-1203119-A1 INCREASING THE WET SLIPPAGE PROPERTIES OF TEXTILE MATERIAL, AND WET-ACTING LUBRICANTS FOR THIS PURPOSE Clariant Finance (BVI) Limited (VG) 2002-05-08 EP disclosed
WO-2001006055-A1 INCREASING THE WET SLIPPAGE PROPERTIES OF TEXTILE MATERIAL, AND WET-ACTING LUBRICANTS FOR THIS PURPOSE CLARIANT FINANCE (BVI) LIMITED (VG) 2001-01-25 WO disclosed
EP-1070781-A1 Increase of wet lubricity of textile materials and wet lubricant CLARIANT INTERNATIONAL LTD. (CH) 2001-01-24 EP disclosed
EP-0091326-A2 Imaging with high aspect ratio tabular grain emulsions and nonplanar support elements EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-10-12 EP disclosed