SCHEMBL643109

SCHEMBL643109

C/C(=C\C1CCCCCC1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.44
GRIK2 Q13002 1/20 0.42
ALDH1A1 P00352 2/20 0.37
GABRA1 P14867 1/20 0.37
TSHR P16473 1/20 0.37
GABRG2 P18507 1/20 0.37
RXRA P19793 1/20 0.37
GABRB3 P28472 1/20 0.37
RXRB P28702 1/20 0.37
GABRB2 P47870 1/20 0.37
RXRG P48443 1/20 0.37
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
HTT P42858 1/20 0.31
NPC1 O15118 1/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8961149 1.00 GRIK1 (0.44) GRIK1GRIK2ALDH1A1GABRA1TSHR
SCHEMBL5489911 1.00 GRIK1 (0.44) GRIK1GRIK2ALDH1A1GABRA1TSHR
SCHEMBL1721398 1.00 GRIK1 (0.44) GRIK1GRIK2ALDH1A1GABRA1TSHR
SCHEMBL36412 1.00 GRIK1 (0.44) GRIK1GRIK2ALDH1A1GABRA1TSHR
SCHEMBL8595697 1.00 GRIK1 (0.44) GRIK1GRIK2ALDH1A1GABRA1TSHR
SCHEMBL156030 1.00 GRIK1 (0.44) GRIK1GRIK2ALDH1A1GABRA1TSHR
SCHEMBL1245246 1.00 GRIK1 (0.44) GRIK1GRIK2ALDH1A1GABRA1TSHR
SCHEMBL1244582 1.00 GRIK1 (0.44) GRIK1GRIK2ALDH1A1GABRA1TSHR
SCHEMBL111090 1.00 GRIK1 (0.44) GRIK1GRIK2ALDH1A1GABRA1TSHR
SCHEMBL154917 1.00 GRIK1 (0.44) GRIK1GRIK2ALDH1A1GABRA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0312228-B2 Polymeric additives for use in adhesive compositions ROHM & HAAS (US) 1997-09-17 EP claimed
EP-3197953-B1 IMPACT-RESISTANT MOULDING MATERIAL WITH IMPROVED CHARACTERISTIC PROFILE EVONIK ROEHM GMBH (DE) 2018-05-23 EP disclosed
EP-3283540-A1 AQUEOUS POLYURETHANE-POLYACRYLATE DISPERSIONS Covestro Deutschland AG (DE) 2018-02-21 EP disclosed
EP-3197953-A1 IMPACT-RESISTANT MOLDING MATERIAL HAVING AN IMPROVED CHARACTERISTICS PROFILE Evonik Röhm GmbH (DE) 2017-08-02 EP disclosed
EP-2786378-B1 HOLOGRAPHIC MEDIUM WITH PROTECTIVE COATING COVESTRO DEUTSCHLAND AG (DE) 2017-05-10 EP disclosed
EP-2704754-B1 HYDROPHILIC POLYURETHANE FOAM WITH LOW VOLUME SWELLING COVESTRO DEUTSCHLAND AG (DE) 2017-03-22 EP disclosed
EP-2978785-B1 IMPACT-RESISTANT PMMA WITH IMPROVED OPTICAL PROPERTIES EVONIK ROEHM GMBH (DE) 2017-03-08 EP disclosed
WO-2016166096-A1 AQUEOUS POLYURETHANE-POLYACRYLATE DISPERSIONS COVESTRO DEUTSCHLAND AG (DE) 2016-10-20 WO disclosed
WO-2016046043-A1 IMPACT-RESISTANT MOLDING MATERIAL HAVING AN IMPROVED CHARACTERISTICS PROFILE EVONIK RÖHM GMBH (DE) 2016-03-31 WO disclosed
EP-2978785-A1 PMMA PROVIDED WITH IMPACT RESISTANCE AND HAVING IMPROVED OPTICAL PROPERTIES Evonik Röhm GmbH (DE) 2016-02-03 EP disclosed
EP-1743363-A2 THERMALLY CURED UNDERCOAT FOR LITHOGRAPHIC APPLICATION FujiFilm Electronic Materials USA, Inc. (US) 2007-01-17 EP disclosed
WO-2006079394-A1 IMPACT-RESISTANT POLY(METH)ACRYLATE MOULDING MASSES WITH HIGH THERMAL STABILITY RÖHM GMBH (DE) 2006-08-03 WO disclosed
US-20050238997-A1 Thermally cured undercoat for lithographic application FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. 2005-10-27 US disclosed
WO-2005089150-A2 THERMALLY CURED UNDERCOAT FOR LITHOGRAPHIC APPLICATION FUJIFILM ELECTRONIC MATERIALS USA INC. (US) 2005-09-29 WO disclosed
EP-1572769-A1 METHOD FOR PRODUCING AQUEOUS DISPERSIONS Röhm GmbH & Co. KG (DE) 2005-09-14 EP disclosed
EP-1572768-A2 CORE AND SHELL PARTICLE FOR MODIFYING IMPACT RESISTANCE OF A MOULDABLE POLY(METH)ACRYLATE MATERIAL Röhm GmbH & Co. KG (DE) 2005-09-14 EP disclosed
WO-2004056893-A1 METHOD FOR PRODUCING AQUEOUS DISPERSIONS Röhm GmbH & Co. KG (DE) 2004-07-08 WO disclosed
WO-2004056892-A2 CORE AND SHELL PARTICLE FOR MODIFYING IMPACT RESISTANCE OF A MOULDABLE POLY(METH)ACRYLATE MATERIAL Röhm GmbH & Co. KG (DE) 2004-07-08 WO disclosed
EP-0552603-B1 Soluble polymers BASF AG (DE) 1996-01-10 EP disclosed
EP-0552603-A1 Soluble polymers BASF Aktiengesellschaft (DE) 1993-07-28 EP disclosed