Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961149 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL643109 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL5489911 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL1721398 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL36412 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL156030 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL1245246 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL1244582 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL111090 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR | |
| SCHEMBL154917 | 1.00 | GRIK1 (0.44) | GRIK1GRIK2ALDH1A1GABRA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590573-B1 | Resin for plastic lens | HITACHI CHEMICAL CO LTD (JP) | 1998-01-07 | — | — | EP | claimed |
| US-4680359-A | CYCLOALIPHATIC METHACRYLATE INTERPOLYMER | ROHM GMBH (DE) | 1987-07-14 | — | — | US | disclosed |