Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4796450 | 0.81 | — | — | |
| SCHEMBL14000460 | 0.78 | NOS1 (0.31) | TSHRCYP3A4CYP2D6NFKB1THPO | |
| SCHEMBL13575444 | 0.78 | TSHR (0.34) | TSHRLMNA | |
| SCHEMBL17082455 | 0.77 | — | — | |
| SCHEMBL12216606 | 0.75 | — | — | |
| SCHEMBL6826865 | 0.75 | — | — | |
| SCHEMBL2382620 | 0.71 | — | — | |
| SCHEMBL11398062 | 0.71 | — | — | |
| SCHEMBL8309234 | 0.71 | — | — | |
| SCHEMBL10522453 | 0.69 | TSHR (0.34) | TSHRTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117122691-A | Intelligent drug carrier with neighborhood effect and pH/reduction sensitive shell crosslinking, and preparation method and application thereof | 华东理工大学 | 2023-11-28 | — | — | CN | claimed |
| CN-117122691-A | Intelligent drug carrier with neighborhood effect and pH/reduction sensitive shell crosslinking, and preparation method and application thereof | 华东理工大学 | 2023-11-28 | — | — | CN | disclosed |
| EP-1154771-A4 | NITROSATED AND NITROSYLATED PROTON PUMP INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED INC (US) | 2005-04-20 | — | — | EP | disclosed |
| EP-1154771-A1 | NITROSATED AND NITROSYLATED PROTON PUMP INHIBITORS, COMPOSITIONS AND METHODS OF USE | Nitromed, Inc. (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000050037-A1 | NITROSATED AND NITROSYLATED PROTON PUMP INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2000-08-31 | — | — | WO | disclosed |
| EP-0291521-A1 | SULFUR-CONTAINING COMPOSITIONS, LUBRICANT, FUEL AND FUNCTIONAL FLUID COMPOSITIONS. | LUBRIZOL CORP (US) | 1988-11-23 | — | — | EP | disclosed |
| WO-1988003552-A2 | SULFUR-CONTAINING COMPOSITIONS, LUBRICANT, FUEL AND FUNCTIONAL FLUID COMPOSITIONS | THE LUBRIZOL CORPORATION (US) | 1988-05-19 | — | — | WO | disclosed |