Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.61 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665718 | 0.90 | MAOB (0.62) | MAOBMAOASCN9AADAMTS4MMP13 | |
| SCHEMBL1672184 | 0.90 | MAOB (0.62) | MAOBMAOASCN9AADAMTS4MMP13 | |
| SCHEMBL2940856 | 0.90 | MAOB (0.62) | MAOBMAOASCN9AADAMTS4MMP13 | |
| Water SCHEMBL1672445 | 0.89 | MAOB (0.61) | MAOBMAOASCN9AADAMTS4MMP13 | |
| Water SCHEMBL1672694 | 0.89 | MAOB (0.61) | MAOBMAOASCN9AADAMTS4MMP13 | |
| SCHEMBL1665416 | 0.89 | MAOB (0.56) | MAOBMAOASCN9AADAMTS4MMP13 | |
| SCHEMBL4540936 | 0.81 | MAOB (0.69) | MAOBMAOASCN9AGRM5PPARA | |
| SCHEMBL4540931 | 0.81 | MAOB (0.69) | MAOBMAOASCN9AGRM5PPARA | |
| SCHEMBL8640665 | 0.80 | MAOB (0.49) | MAOBMAOASCN9ABCHE | |
| Hydrochloric Acid SCHEMBL31070308 | 0.80 | MAOB (0.68) | MAOBMAOASCN9ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1589959-A2 | METHODS OF TREATING LOWER URINARY TRACT DISORDERS USING SODIUM CHANNEL MODULATORS | Dynogen Pharmaceuticals Inc. (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004066990-A2 | METHODS OF TREATING LOWER URINARY TRACT DISORDERS USING SODIUM CHANNEL MODULATORS | DYNOGEN PHARMACEUTICALS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |