Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.56 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431395 | 0.89 | MAOB (0.61) | MAOBMAOASCN9AADAMTS4MMP13 | |
| SCHEMBL1672184 | 0.88 | MAOB (0.62) | MAOBMAOASCN9AADAMTS4MMP13 | |
| SCHEMBL1665718 | 0.88 | MAOB (0.62) | MAOBMAOASCN9AADAMTS4MMP13 | |
| SCHEMBL2940856 | 0.88 | MAOB (0.62) | MAOBMAOASCN9AADAMTS4MMP13 | |
| Water SCHEMBL1672445 | 0.87 | MAOB (0.61) | MAOBMAOASCN9AADAMTS4MMP13 | |
| Water SCHEMBL1672694 | 0.87 | MAOB (0.61) | MAOBMAOASCN9AADAMTS4MMP13 | |
| SCHEMBL8640665 | 0.78 | MAOB (0.49) | MAOBMAOASCN9A | |
| SCHEMBL8637848 | 0.77 | MAOB (0.48) | MAOBMAOASCN9A | |
| SCHEMBL4540936 | 0.77 | MAOB (0.69) | MAOBMAOASCN9AGRM5PPARA | |
| SCHEMBL4540931 | 0.77 | MAOB (0.69) | MAOBMAOASCN9AGRM5PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047767-A1 | NOVEL POLYMORPHIC FORMS OF (S)-2-[-4-(3-FLUORO-BENZYLOXY)-BENZYLAMINO]-PROPIONAMIDE MESYLATE SALT AND PROCESSES OF MANUFACTURING THEREOF | MERCK PATENT GMBH (DE) | 2011-04-28 | — | — | WO | disclosed |
| EP-2314569-A1 | Novel polymorphic forms of (S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propionamide mesylate salt and processes of manufacturing thereof | Merck Patent GmbH (DE) | 2011-04-27 | — | — | EP | disclosed |