Quinoxaline

Quinoxaline

SCHEMBL6431397

Fc1ccc(-c2nc3ccccc3nc2-c2ccc(F)cc2)cc1.c1ccc2nccnc2c1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 14/20 0.73
MAPK10 P53779 2/20 0.73
TGFBR1 P36897 1/20 0.50
ADORA2A P29274 1/20 0.49
KDM4E B2RXH2 1/20 0.48
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29405271 0.90 MAPK14 (0.81) MAPK14MAPK10ADORA2AKDM4ELMNA
SCHEMBL71619 0.90 MAPK14 (0.81) MAPK14MAPK10ADORA2AKDM4ELMNA
SCHEMBL27962380 0.88 MAPK14 (0.78) MAPK14MAPK10ADORA2AKDM4ELMNA
SCHEMBL29596631 0.88 MAPK14 (0.78) MAPK14MAPK10ADORA2AKDM4ELMNA
SCHEMBL29767839 0.88 MAPK14 (0.78) MAPK14MAPK10ADORA2AKDM4ELMNA
SCHEMBL28252524 0.88 MAPK14 (0.78) MAPK14MAPK10ADORA2AKDM4ELMNA
SCHEMBL28215884 0.86 MAPK14 (0.75) MAPK14MAPK10ADORA2AKDM4ELMNA
SCHEMBL17656946 0.82 MAPK14 (0.70) MAPK14MAPK10ADORA2AKDM4ELMNA
Phenanthroline SCHEMBL28263054 0.81 MAPK14 (0.63) MAPK14MAPK10TGFBR1KDM4ELMNA
SCHEMBL14819322 0.81 TDP1 (0.75) MAPK14MAPK10ADORA2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050191527-A1 Organometallic compound containing quinoxaline structure and light emitting element SANYO ELECTRIC CO., LTD. (JP) 2005-09-01 US disclosed